The pair were in the light-rigid truck when it lost control and tipped on the Gwydir Highway, just out of Gravesend, shortly after 7am.

Ambulance NSW confirmed paramedics treated two women at the scene, who managed to climb from the tipped truck.

A woman, aged about 40, was treated for a leg injury, while a second woman, believed to be aged in her 20s suffered a head injury.

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Both women were transported to Moree hospital in a stable condition with minor injuries, the Ambulance NSW spokesperson said.

Fire and Rescue NSW crews were deployed from Warialda, along with the NSW Rural Fire Service, to the crash site after a small amount of oil and diesel spilled from the truck onto the roadway.

The wreckage blocked both lanes before traffic controls were put in place by emergency services and Gwydir Shire Council to move people around the scene.

Fire and Rescue NSW said a heavy vehicle salvage crew was tasked from Moree to move the vehicle and clear the roadway.

The area was rendered safe within hours.