The pair, aged 20 and 25, are in custody and set to front a Tamworth court on Thursday morning. They face a raft of charges and up to 20 years behind bars if found guilty of ongoing drug supply.

Strike Force Numboidard was launched in August by Oxley police and rural crime investigators, and backed by Gunnedah general duties officers.

The police had been trying to home in on those involved in the supply of methylamphetamine, cannabis and MDMA in Gunnedah and surrounding towns.

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After three-and-a-half months of investigations, they pounced on Wednesday, seizing drugs and what they claim is an illegal weapon.

Police will allege they uncovered 28 grams of methylamphetamine at the Werris Creek home.

A 20-year-old Boggabri man is accused of two counts of ongoing drug supply, participating in a criminal group and possessing a prohibited drug.

A 25-year-old man is accused of two counts of supplying drugs; ongoing supply; participating in a criminal group; aggravated deposit litter; as well as hunting in a state forest.

The pair were refused bail and will spend the night in custody, ahead of bail hearings on Thursday.

A 62-year-old man remains on bail after his arrest in Gunnedah in late November.

Police raided a property and seized what they allege is 460g of cannabis leaf; 87g of GBL, which is a depressant and a precursor to the drug GHB; as well as 77 testosterone tablets.

The man faces several drug-related offences and is due back in court at a later date.

On Wednesday, police said the investigation had started with them receiving information on rural crime, and widened into drug activities.

Senior police have warned further arrests are expected and investigations continue.

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