The woman was behind the wheel of a Ford Falcon when it collided with a second Ford Falcon on Yetman Rd, near Fullers Ln, about 2.20pm.

She suffered critical injuries and died at the scene.

A 37-year-old woman was driving the second Falcon, and had two passengers inside, aged 37 and 43.

All three were taken to Inverell hospital in a stable condition.

The 37-year-old male suffered a fractured ankle and sternum and was airlifted by the Westpac Rescue Helicopter to Tamworth hospital for further treatment.

The road was closed for sometime but re-opened on Thursday night.

Police said early investigations suggest both vehicles were travelling on Yetman Road when one vehicle crossed into the path of the second vehicle and collided head-on.

Police are now preparing a report for the coroner.

ONE WOMAN has died and three other people have been taken to hospital after an horrific crash on the outskirts of Inverell.

Investigators are piecing together the moments before the two cars collided at the intersection of Yetman Rd and Fullers Ln shortly before 3pm on Thursday.

A woman, believed to be aged in her 70s, died at the scene, about 5km from town.

Police and paramedics arrived to find the woman unconscious and Fairfax Media has been told crews performed CPR on the woman but she died from her injuries.

The VRA, SES and Fire and Rescue NSW crews were also deployed to the scene after three other people were trapped inside one of the wreckages.

A spokesperson for Ambulance NSW said paramedics treated two men and a woman at the scene.

“A 40-year-old female sustained abdominal and ankle pain,” the spokesperson said.

“A 45-year-old had severe chest pain as well as shoulder and thumb injuries.”

The spokesperson said a second man, also aged 45, suffered severe leg injuries, lacerations and had chest and abdominal pain.

All three patients were assessed at the scene and taken to Inverell hospital in a stable condition before the Westpac Rescue Helicopter was tasked from Tamworth to collect one of the injured.

The crash shut the road for several hours with specialist police called in to comb the crash scene. 

The cause is still under investigation and a report will now be prepared for the coroner.

EMERGENCY services are working to free three people trapped in a car in Inverell.

Police, paramedics and rescue crews are assessing three patients inside a car at the crash on Yetman Road, cross of Fullers Lane.

The crash occurred shortly before 3pm.

Emergency services are at the scene and the road has been closed.