Virgin Australia will reduce its overnight Tamworth-Sydney services from six flights a week to three at the end of October, following a re-allocation of landing slots at Sydney Airport.

Tamworth Business Chamber president Lia Mahony said the reduced flights would make it more difficult for new business to move into the area.

“It's also going to make it harder for local businesses expanding,” Ms Mahony said.

“It can prevent making new contacts, sourcing new equipment, services and products, and recruitment.

“I've flown down for interviews with people applying for a position in Tamworth.”

Tamworth MP Kevin Anderson said he was organising meetings with federal Transport Minister Darren Chester and NSW Infrastructure Minister Andrew Constance.

“I don't want to see regional NSW or regional airlines squeezed out of Sydney Airport,” Mr Anderson said.