The simultaneous protests took place at Santos' operation centre, the Leewood wastewater treatment plant and a truck parked at a rest stop on the Newell Highway.

Coonabarabran agricultural teacher and sixth-generation farmer, Michelle Webb, locked herself to the gate of the Leewood facility for more than two hours.

"This is not how I'd choose to spend my morning four days before Christmas, but it's urgent that we stop the threat of coal seam gas before it takes over like it has in Queensland," Ms Webb said.

"You cannot have the coal seam gas industry and respect our precious water resources you just cannot have both."

Coonabarabran mother and small business owner, Nicole Hunter, was locked to the gate of Santos' Narrabri operations centre and said she was determined to protect the future of the region for her three young daughters.

"The most important gift I can ever give my children is a healthy and sustainable future," Ms Hunter said.

Ms Webb and Ms Hunter unlocked themselves at the request of police, because they believed their point had made been made.

Two people locked-on to the parked truck, which is transport- ing infrastructure to the Leewood facility.

A 21-year old Brisbane man started the protest before being replaced by Coonabarabran resident and ex- government ecologist David Paull.

The police came and went from the scene at about 9.30am.

The Leader understands Mr Paull continued the protest overnight with a group of supporters.

"Gasfields do not belong in anyone's backyard, not on farms, important bushland nor ground water recharge areas once aquifers are destroyed they can't be fixed," Mr Paull said.

Santos Narrabri operations manager Todd Dunn said the protests had a "very minor" impact on Santos' activities.

"While Santos respects the right of people to partake in peaceful protests, these protests are largely targeting our plans to desalinate the water from our operations so that it can be beneficially reused for a variety of uses including irrigation, "Mr Dunn said.

"Santos has all approvals necessary to carry out this work.

"We remain confident we have strong support in the local community and are very proud of the work we do near Narrabri."

The lock-ons were the latest in a number of protests held by anti-CSG groups in the Pilliga, but Yes2Gas spokeswoman Louise Tout said the protesters do not represent the entire Narrabri shire population.

Yes2Gas represents the people in the region who support the project and the organisation said the agricultural industry and the gas industry could co-exist.

"It's going to be good for employment opportunities for locals and will naturally boost our local economy," Ms Tout said.

"Overall the introduction of a new industry to our town is a good thing and it will diversify our community we are very fortunate to have this opportunity."