Malcolm Naden, who gained notoriety as a bush fugitive in more than six years on the run, has been charged with the murder of his cousin Lateesha Nolan.
Naden, 38, was told of the fresh charges during a video court appearance at Central Local Court in Sydney on Tuesday.
Naden had previously been charged with the 2005 murder of Kristy Scholes and two counts of aggravated indecent assault on a 12-year-old girl.
He was also charged with the attempted murder of a police officer at Nowendoc on December 7, 2011.
Ms Nolan disappeared after dropping two of her children off at her grandparents' home in west Dubbo and her body has not been found.
Speaking outside court, NSW homicide squad commander Michael Willing said police believed they had enough evidence to lay the fresh charge.
"In relation to Lateesha's body we will continue to investigate the matter and if there is sufficient evidence to locate it we will certainly follow it," Detective-Superintendent Willing told reporters.