Three road ambulances along with an air ambulance were tasked  the single-car rollover which happened on the Kamillaroi Highway about 1.30pm.

Initial reports to paramedics said a four-wheel-drive towing a caravan had rolled on the highway.

A woman in her 60s is believed to trapped in the car, while another man is believed to be ejected from the vehicle.They're being treated by Ambulance crews at the scene.